COMPOSITIONS COMPRISING A FATTY ACID OIL MIXTURE COMPRISING EPA AND DHA IN FREE ACID FORM, A SURFACTANT, AND A STATIN

Preconcentrates comprising a fatty acid oil mixture, at least one surfactant, and at least one statin or pharmaceutically acceptable salt, hydrate, solvate, or complex thereof, and methods and uses thereof are disclosed. The preconcentrates are capable of forming a self-nanoemulsifying drug delivery...

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Bibliographic Details
Main Authors OLESEN, PREBEN HOULBERG, HUSTVEDT, SVEIN OLAF, BERGE, GUNNAR, KLAVENESS, JO ERIK JOHNSRUD
Format Patent
LanguageEnglish
French
German
Published 09.04.2014
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Preconcentrates comprising a fatty acid oil mixture, at least one surfactant, and at least one statin or pharmaceutically acceptable salt, hydrate, solvate, or complex thereof, and methods and uses thereof are disclosed. The preconcentrates are capable of forming a self-nanoemulsifying drug delivery system (SNEDDS), a self-microemulsifying drug delivery system (SMEDDS), or self-emulsifying drug delivery systems (SEDDS) in an aqueous solution.
Bibliography:Application Number: EP20110823130