1H-Benzo[d]imidazol-5-yl compounds and composition for treating inflammatory diseases

Provided are heterocyclic compounds, having effects of treating and preventing inflammatory diseases and treating skin wounds, and particularly, exhibiting effects of recovering disrupted skin barriers, mitigating inflammation, and pruritus. Also, a composition containing the compound as an effectiv...

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Main Authors PARK, BYEONG DEOG, PARK, TAE KYO, WOO, SUNG HO, JEON, JEONG EUN, GWAK, HYUNG SUB, KIM, YONG ZU, KIM, UK IL, YUN, JOUNG YUL, JEONG, SE KYOO, CHOI, HYUNG MOOK, LEE, DAE YON, LEE, HYANG SOOK
Format Patent
LanguageEnglish
French
German
Published 03.07.2013
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Summary:Provided are heterocyclic compounds, having effects of treating and preventing inflammatory diseases and treating skin wounds, and particularly, exhibiting effects of recovering disrupted skin barriers, mitigating inflammation, and pruritus. Also, a composition containing the compound as an effective component can be used to mitigate vairous inflammatory diseases and protease activated receptor-2 (PAR-2)-overexpressed diseases, and can be particulalry used as a composition having an anti-inflmammatory function in inflammatory skin diseases including atopic dermatitis and the like, by inhibiting PAR-2 activity.
Bibliography:Application Number: EP20110820193