RECOMBINANT MICROORGANISMS, METHODS FOR PREPARING VACCINE STRAINS, ANTIGENS, AND VECTOR VACCINE COMPOSITIONS OF SAME, USES THEREOF, AND RELATED ANTIBODIES, DIAGNOSTIC KIT, AND TREATMENT AND/OR PROPHYLACTIC METHODS

The present invention provides live recombinant microorganisms such as prokaryote organisms, particularly enterobacteria, preferably Salmonella enterica, containing SEQ. ID. no. 1 and SEQ. ID. no. 2 capable of expressing VapG and/or VapA/VapG lipoproteins (SEQ. ID. no. 3 and SEQ. ID. no. 4), optiona...

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Bibliographic Details
Main Authors FERRAZ COLBACHINI, LUCIANA, RUSCA CORREO PORTO, ANA CAROLINA, ALMEIDA CARDOSO, SILVIA, DE OLIVEIRA PEREIRA, ALINE FERREIRA, GOMES SOARES, SANDRO, DOS SANTOS FERRAZ, LUIZ EDUARDO, EBERT SEIXAS, HANNA, PAIVA, HELDER HENRIQUE, PEREIRA RUAS, LUCIANA, ROQUE ANTUNES BARREIRA, MARIA CRISTINA
Format Patent
LanguageEnglish
French
German
Published 02.04.2014
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES USING MICROORGANISMS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
TESTING
VINEGAR
WINE
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Summary:The present invention provides live recombinant microorganisms such as prokaryote organisms, particularly enterobacteria, preferably Salmonella enterica, containing SEQ. ID. no. 1 and SEQ. ID. no. 2 capable of expressing VapG and/or VapA/VapG lipoproteins (SEQ. ID. no. 3 and SEQ. ID. no. 4), optionally in combination with other active ingredients, methods for preparing vaccine strains, antigens (SEQ. ID. no. 3 and SEQ. ID. no. 4) and vaccine compositions, preferably vectored vaccines. Additionally, the present patent application relates to the use of the vaccine vectors in the preparation of pharmaceutical compositions, particularly vaccines indicated for the prevention and/or treatment of infections by Rhodococcus equi, its antibodies and/or antisera, diagnostic kits and methods for the prophylaxis and/or treatment of infections by R. equi.
Bibliography:Application Number: EP20110809093