DETECTION AND QUANTIFICATION OF VITAMIN D METABOLITES USING AN ALKYLAMINE TO FORM STABLE ADDUCTS FOR MASS SPECTROMETRIC ANALYSIS

The invention describes a method of determining the amount of an analyte in a sample wherein the analyte comprises one or more vitamin D metabolites; comprising the steps of; contacting the analyte with an alkylamine to form an alkylamine adduct; subjecting the adduct to a MS technique to determine...

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Bibliographic Details
Main Authors MOLLOY, BILLY J, CALTON, LISA J
Format Patent
LanguageEnglish
French
German
Published 08.05.2013
Subjects
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Summary:The invention describes a method of determining the amount of an analyte in a sample wherein the analyte comprises one or more vitamin D metabolites; comprising the steps of; contacting the analyte with an alkylamine to form an alkylamine adduct; subjecting the adduct to a MS technique to determine the amount of the adduct; and calculating the amount of the analyte equivalent to the amount of the adduct.
Bibliography:Application Number: EP20110730394