Long term sustained release pharmaceutical composition containing aqueous suspension of bisphosphonate

The invention relates to a pharmaceutical composition suitable for injection as an aqueous suspension for sustained release of a bisphosphonate drug, the composition comprising: a sosoloid containing a salt of a bisphosphonate drug; and a salt of a pentavalent phosphorus oxoacid, the sosoloid having...

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Bibliographic Details
Main Authors XIE, KEVIN, LUO, MARY ZIPING, DING, JIE FEI, ZHANG, JACK, YONGFENG, FEI, DINGYUAN
Format Patent
LanguageEnglish
French
German
Published 23.01.2013
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to a pharmaceutical composition suitable for injection as an aqueous suspension for sustained release of a bisphosphonate drug, the composition comprising: a sosoloid containing a salt of a bisphosphonate drug; and a salt of a pentavalent phosphorus oxoacid, the sosoloid having a solubility in saline of less than 0.05% by weight as bisphosphonic acid for use as a medicament and for use in the prevention or treatment of a bone disease in a patient, in particular osteoporosis.
Bibliography:Application Number: EP20120186963