Method of making a stent graft by electrospinning

• Main Authors: Magnuson, Mark A, Chambers, Sean E, Frye, Mark R, Vad, Siddharth
• Format: Patent
• Language: English; French; German
• Published: 18.04.2018
• Subjects: AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING; BANDAGES, DRESSINGS OR ABSORBENT PADS; BRAIDING; COTTON-WOOL; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS,NON-WOVEN FABRICS; FILTERS IMPLANTABLE INTO BLOOD VESSELS; FIRST-AID KITS; FOMENTATION; HUMAN NECESSITIES; HYGIENE; KNITTING; LACE-MAKING; MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARYMATERIAL; MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OFARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES ORRIBBONS; MEDICAL OR VETERINARY SCIENCE; NATURAL OR ARTIFICIAL THREADS OR FIBRES; NON-WOVEN FABRICS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; PERFORMING OPERATIONS; PROSTHESES; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDEDFOR; SHAPING OR JOINING OF PLASTICS; SPINNING; TEXTILES; TRANSPORTING; TREATMENT OR PROTECTION OF EYES OR EARS; TRIMMINGS; WADDING; WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE, IN GENERAL

In a method for making a graft layer (24) having at least two layers with different porosities, the two layers are applied by an electrospinning apparatus (10). The parameters of the electrospinning are varied when applying the first and second layers in order to achieve an outer layer that is less porous than the inner layer. Needles with different lumina are employed.