Benethamine salt forms of atorvastatin

Novel benethamine salt forms of [R-(R*,R*)]-2-(4-fluorophenyl)-beta, delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid characterised by their X-ray powder diffraction pattern and solid-state NMR spectra are described, as well as methods for their prepar...

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Bibliographic Details
Main Authors CAMPETA, ANTHONY, MICHAEL, LEONARD, JASON, A, KRZYZANIAK, JOSEPH, F
Format Patent
LanguageEnglish
French
German
Published 15.05.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Novel benethamine salt forms of [R-(R*,R*)]-2-(4-fluorophenyl)-beta, delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid characterised by their X-ray powder diffraction pattern and solid-state NMR spectra are described, as well as methods for their preparation and pharmaceutical compositions of the same , which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia, and Alzheimer's disease.
Bibliography:Application Number: EP20120181391