PHENYL-HETEROARYL DERIVATIVES AND METHODS OF USE THEREOF

The present invention provides phenyl-heteroaryl derivatives of Formula (I) and pharmaceutically acceptable salts thereof These compounds are useful in the treatment of RAGE-mediated diseases such as Alzheimer's Disease. The present invention further relates to methods for the preparation of co...

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Main Authors SUNDERMANN, KURT, RAO, MOHAN, GUPTA, SUPARNA, JONES, DAVID, BANNER, WILLIAM, KENNETH, BONDLELA, MURALIDHAR, WANG, PINGZHEN, HARI, ANITHA, QABAJA, GHASSAN, GOHIMUKKULA, DEVI, REDDY, GOWDA, RAJU, BORE, ZHU, JEFF, JIQUN, ANDREWS, ROBERT, C, COOPER, JEREMY, T
Format Patent
LanguageEnglish
French
German
Published 29.07.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides phenyl-heteroaryl derivatives of Formula (I) and pharmaceutically acceptable salts thereof These compounds are useful in the treatment of RAGE-mediated diseases such as Alzheimer's Disease. The present invention further relates to methods for the preparation of compounds of Formula (I) and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising such compounds, and the use of such compounds and/or pharmaceutical compositions in treating RAGE-mediated diseases.
Bibliography:Application Number: EP20110745116