MACROCYCLES AS FACTOR XIA INHIBITORS

The present invention provides synthetic intermediates useful in the preparation of compounds of Formula (I) or a stereoisomer, a tautomer, or a pharmaceutically acceptable salt thereof, wherein all the variables are as defined herein. These compounds are selective Factor Xia inhibitors or dual inhi...

Full description

Saved in:
Bibliographic Details
Main Authors CORTE, James, R, QUAN, Mimi, L, DECICCO, Carl, P, WANG, Cailan
Format Patent
LanguageEnglish
French
German
Published 02.05.2018
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online AccessGet full text

Cover

More Information
Summary:The present invention provides synthetic intermediates useful in the preparation of compounds of Formula (I) or a stereoisomer, a tautomer, or a pharmaceutically acceptable salt thereof, wherein all the variables are as defined herein. These compounds are selective Factor Xia inhibitors or dual inhibitors of fXIa and plasma kallikrein.
Bibliography:Application Number: EP20110704895