PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS mTOR INHIBITORS

The present invention provides Pyrazolopyrimidine Compounds of Formula (I): wherein L, T, Z, U, V, W, R3, R6, R7, R8, and m are as defined herein, and pharmaceutically acceptable salts of such Pyrazolopyrimidine Compounds. The Pyrazolopyrimidine Compounds are useful in the treatment of cancer and ot...

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Main Authors TANG, Shuyi, CURRAN, Patrick, J, SIDDIQUI, M. Arshad, ZHAO, Lianyun, VITHARANA, Lalanthi Dilrukshi, PATEL, Mehul, F, MCRINER, Andrew, DANIELS, Matthew Hersh, LIU, Duan, REDDY, Panduranga Adulla P, MANDAL, Amit, K, ANGELES, Angie, R, BELANGER, David, B, DAI, Chaoyang, NAN, Yang, MANSOOR, Umar Faruk, MENG, Zhaoyang, YANG, Liping
Format Patent
LanguageEnglish
French
German
Published 28.11.2012
Subjects
AGRICULTURE
ANIMAL HUSBANDRY
BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
PEST REPELLANTS OR ATTRACTANTS
PLANT GROWTH REGULATORS
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF
TRAPPING
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Summary:The present invention provides Pyrazolopyrimidine Compounds of Formula (I): wherein L, T, Z, U, V, W, R3, R6, R7, R8, and m are as defined herein, and pharmaceutically acceptable salts of such Pyrazolopyrimidine Compounds. The Pyrazolopyrimidine Compounds are useful in the treatment of cancer and other diseases or disorders wherein mTOR is deregulated.
Bibliography:Application Number: EP20110735040