Aromatic sulfone compounds useful in the treatment of central nervous disorders

The present invention relates to novel sulfone compounds as 5-HT6 receptor ligands of the formula (I), and their derivatives, prodrugs, tautomers, stereoisomers, polymorphs, solvates, hydrates, metabolites, N-oxides, pharmaceutically acceptable salts and compositions containing them. The present inv...

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Main Authors CHINDHE, ANIL, KASHINATH, KAMBHAMPATI, RAMA, SASTRI, JASTI, VENKATESWARLU, REBALLI, VEENA, NIROGI, RAMAKRISHNA, AHMAD, ISHTIYAQUE, ABRAHAM, RENNY, SHINDE, ANIL, KARBHARI, NAMALA, RAMBABU, MULLA, MOHAMAD, SADIK, ABDULHAMID, BADANGE, RAJESH, KUMAR
Format Patent
LanguageEnglish
French
German
Published 14.11.2012
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to novel sulfone compounds as 5-HT6 receptor ligands of the formula (I), and their derivatives, prodrugs, tautomers, stereoisomers, polymorphs, solvates, hydrates, metabolites, N-oxides, pharmaceutically acceptable salts and compositions containing them. The present invention also relates to a process for the preparation of above said novel compounds, and their derivatives, prodrugs, tautomers, stereoisomers, polymorphs, solvates, hydrates, metabolites, N-oxides, pharmaceutically acceptable salts and compositions containing them. These compounds are useful in the treatment/prevention of various disorders that are related to 5-HT6 receptor functions.
Bibliography:Application Number: EP20100725883