TRANSGENIC PIG IN WHICH HO-1 GENES AND TNFR1-FC GENES ARE SIMULTANEOUSLY EXPRESSED, AND METHOD FOR PRODUCING SAME

The present invention relates to a method for producing a transgenic pig in which immune rejection response is inhibited, and in which human HO-1 genes and TNFR1-Fc fusion genes are simultaneously expressed. The present invention also relates to a transgenic pig for organ transplantation, which is p...

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Main Authors KOO, OK JAE, KANG, JUNG TAEK, LEE, BYEONG CHUN, JANG, GOO, HWANG, JONG IK, YANG, JAESEOK, CHO, BUM RAE, AHN, CURIE, KWON, DAE KEE
Format Patent
LanguageEnglish
French
German
Published 07.11.2012
Subjects
AGRICULTURE
ANIMAL HUSBANDRY
BEER
BIOCHEMISTRY
CARE OF BIRDS, FISHES, INSECTS
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
NEW BREEDS OF ANIMALS
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR
SPIRITS
TRAPPING
VINEGAR
WINE
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Summary:The present invention relates to a method for producing a transgenic pig in which immune rejection response is inhibited, and in which human HO-1 genes and TNFR1-Fc fusion genes are simultaneously expressed. The present invention also relates to a transgenic pig for organ transplantation, which is produced by the method, and in which immune rejection response is inhibited. The present invention also relates to a somatic-cell-donating cell strain for producing the transgenic pig, and to a method for producing organs, from the transgenic pig, in which the immune rejection response in inhibited.
Bibliography:Application Number: EP20100841175