NOVEL 3-HYDROXY-5-ARYLISOTHIAZOLE DERIVATIVE
[Problem] To provide a GPR40 activating agent having, as an active ingredient, a novel compound having a GPR40 agonist action, a salt of the compound, a solvate of the salt or the compound, or the like, particularly, an insulin secretagogue and a prophylactic and/or therapeutic agent against diabete...
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Main Authors | , , , , |
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Format | Patent |
Language | English French German |
Published |
31.10.2012
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Subjects | |
Online Access | Get full text |
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Summary: | [Problem] To provide a GPR40 activating agent having, as an active ingredient, a novel compound having a GPR40 agonist action, a salt of the compound, a solvate of the salt or the compound, or the like, particularly, an insulin secretagogue and a prophylactic and/or therapeutic agent against diabetes, obesity, or other diseases. [Means of solving the problem] A compound of Formula (I):
(where n is 0 to 2; p is 0 to 4; j is 0 to 3; k is 0 to 2; a ring A is an aryl group which is optionally substituted with L or a heterocyclic group which is optionally substituted with L; a ring B is a benzene ring, a pyridine ring, or a pyrimidine ring; X is O, S, -NR 7 -; and R 1 to R 7 are specific groups),
a salt of the compound, or a solvate of the salt or the compound. |
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Bibliography: | Application Number: EP20100839599 |