COMPOUNDS, PREPARATIONS AND USES THEREOF

The present invention provides novel compounds of the Formula I, pharmaceutical compositions comprising such compounds and methods for using such compounds as agents or drugs for inhibiting perforin activity and for treating a subject at risk of or susceptible to a disease or disorder, or having a d...

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Bibliographic Details
Main Authors DENNY, WILLIAM ALEXANDER, LYONS, DANI MICHELLE, SMYTH, MARK JOHN, TRAPANI, JOSEPH ALBERT, SPICER, JULIE ANN, HUTTUNEN, KRISTIINA MARIA
Format Patent
LanguageEnglish
French
German
Published 10.07.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides novel compounds of the Formula I, pharmaceutical compositions comprising such compounds and methods for using such compounds as agents or drugs for inhibiting perforin activity and for treating a subject at risk of or susceptible to a disease or disorder, or having a disease or disorder associated with undesirable perforin activity.
Bibliography:Application Number: EP20100838424