USE OF SECRETED PHOSPHOLIPASES A2 IN THE DIAGNOSIS AND TREATMENT OF MALARIA

The present invention relates to an in vitro method of diagnosis of a Plasmodium infection in a subject, by measuring the serum concentration of at least one secreted phospholipase A2 selected from the group consisting of GIIF, GV and GX sPLA2S, in said subject, from a blood sample. It also relates...

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Bibliographic Details
Main Authors DEREGNAUCOURT, CHRISTIANE, LAMBEAU, GÉRARD, GUILLAUME, CAROLE, SCHREVEL, JOSEPH
Format Patent
LanguageEnglish
French
German
Published 21.05.2014
Subjects
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Summary:The present invention relates to an in vitro method of diagnosis of a Plasmodium infection in a subject, by measuring the serum concentration of at least one secreted phospholipase A2 selected from the group consisting of GIIF, GV and GX sPLA2S, in said subject, from a blood sample. It also relates to a kit for carrying out said method and pharmaceutical compositions comprising a recombinant mammal GIIF, GV or GX sPLA2.
Bibliography:Application Number: EP20100805642