CONFORMABLE BARRIER SHEET, METHODS, AND DEVICE

• Main Authors: KLUGE, BRUCE D, BEST, WILLIAM G, KOLB, WILLIAM BLAKE, DAVID, MOSES M, MANALO, DANIEL O, GORDON, RYAN D
• Format: Patent
• Language: English; French; German
• Published: 13.11.2013
• Subjects: AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F,C08G; CHEMICAL SURFACE TREATMENT; CHEMISTRY; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATIONOR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY IONIMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; COATING MATERIAL WITH METALLIC MATERIAL; COATING METALLIC MATERIAL; COMPOSITIONS BASED THEREON; DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY; DIFFUSION TREATMENT OF METALLIC MATERIAL; GENERAL PROCESSES OF COMPOUNDING; HUMAN NECESSITIES; HYGIENE; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION INGENERAL; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC MACROMOLECULAR COMPOUNDS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THESURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; THEIR PREPARATION OR CHEMICAL WORKING-UP; WORKING-UP

A conformable barrier sheet comprising a polymeric film having a tensile elongation at least 2 fold greater than a polyethylene terephthalate film of equal dimensions and under an equal load; a planarization layer; and a plasma-deposited amorphous glass layer comprising silicon, carbon, and hydrogen; wherein the planarization layer is disposed on the polymeric film, the amorphous glass layer is deposited on the planarization layer, and wherein the barrier sheet is sufficiently conformable that after undergoing a tensile elongation within the range of more than 2% to 20%, the barrier sheet has a moisture vapor transmission rate essentially unchanged compared with prior to being elongated, a method of making the conformable barrier sheet, a transdermal device comprising the conformable barrier sheet, a method of delivering a drug to a mammal using the device, and a method of protecting an article using the conformable barrier sheet are provided.