COMPOSITION FOR INDUCING TISSUE REGENERATION BY ACTIVATING PLATELET-RICH PLASMA (PRP), AND METHOD FOR MANUFACTURING SAME

• Main Authors: YU, JIUL, KIM, JANG-HOON, JANG, JAE-DEOG, PARK, HYUN-SHIN, PARK, JU-HEE, LEE, SAE-BOM, JANG, CHEONG-HO, KIM, HUN
• Format: Patent
• Language: English; French; German
• Published: 01.10.2014
• Subjects: BANDAGES, DRESSINGS OR ABSORBENT PADS; BEER; BIOCHEMISTRY; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; ENZYMOLOGY; FILTERS IMPLANTABLE INTO BLOOD VESSELS; FIRST-AID KITS; FOMENTATION; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METALLURGY; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; PROSTHESES; SPIRITS; TREATMENT OR PROTECTION OF EYES OR EARS; VINEGAR; WINE

Disclosed is a composition for inducing tissue regeneration by activating platelet rich plasma (PRP) with a calcium chloride solution and type I collagen, and a method of manufacturing the same. The disclosed method includes the steps of: separating PRP from whole blood; mixing the PRP with a calcium chloride solution; and mixing the mixture of the PRP and the calcium chloride solution with type I collagen. The disclosed composition may have a gel-type of formation containing PRP, and may be transplanted to any lesion in need of tissue regeneration in cases such as bone defect treatment and wound healing, and accordingly, PRP may be activated to induce a growth factor which is useful for tissue regeneration from PRP gel to conveniently and quickly achieve effective tissue regeneration. Accordingly, the disclosed method is very useful in enhancing the credibility of applying PRP to lesions and presenting a good image to consumers.