Antineoplasic compounds and pharmaceutical compositions thereof

Chemical compounds identified by in silico molecular modelling, and having an structure that allows the blocking of the phosphorylation event, through the interaction of such compounds with the phosphorylation domain or its milieu in the substrates of the Casein Kinase 2 enzyme. This invention compr...

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Main Authors VERA ALVAREZ, ROBERTO, MAZOLA REYES, YULIET, PEREA RODRIGUEZ, SILVIO ERNESTO, DE LA NUEZ VEULENS, ANIA, MUSACCHIO LASA, ALEXIS, UBIETA GOMEZ, RAIMUNDO, ACEVEDO CASTRO, BORIS ERNESTO, RODRIGUEZ FERNANDEZ, ROLANDO EDUARDO
Format Patent
LanguageEnglish
French
German
Published 11.07.2012
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Chemical compounds identified by in silico molecular modelling, and having an structure that allows the blocking of the phosphorylation event, through the interaction of such compounds with the phosphorylation domain or its milieu in the substrates of the Casein Kinase 2 enzyme. This invention comprises also the pharmaceutical compositions containing such compounds, and their use in the preparation of medicines for the treatment of diseases related with neoplasic processes.
Bibliography:Application Number: EP20120160680