PYRIMIDINES AS HEPCIDINE ANTAGONISTS

The present invention relates to new hepcidin antagonists, pharmaceutical compositions containing them and the use thereof as a drug, in particular for the treatment of iron metabolism disorders such as, in particular, iron deficiency diseases and anaemia, in particular anaemia associated with chron...

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Main Authors BUHR, WILM, DÜRRENBERGER, FRANZ, CORDEN, VINCENT, ANTHONY, DAVENPORT, TARA, RIDGILL, MARK PETER, COURTNEY, STEPHEN, MARTIN, FUNK, FELIX, SLACK, MARK, JAEGER, STEFAN, BAINBRIDGE, JULIA, MARIE, BURCKHARDT, SUSANNA, GEISSER, PETER, OTTO, YAU, WEI, TSUNG, YARNOLD, CHRISTOPHER, JOHN
Format Patent
LanguageEnglish
French
German
Published 28.10.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to new hepcidin antagonists, pharmaceutical compositions containing them and the use thereof as a drug, in particular for the treatment of iron metabolism disorders such as, in particular, iron deficiency diseases and anaemia, in particular anaemia associated with chronic inflammatory disease (ACD: anaemia of chronic disease and AI: anaemia of inflammation).
Bibliography:Application Number: EP20100747859