CATHEPSIN C INHIBITORS

Disclosed are 4-amino-2-butenamides of Formula (I) having pharmacological activity, pharmaceutical compositions containing them, and methods for the treatment of diseases mediated by the cathepsin C enzyme such as chronic obstructive pulmonary disease.

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Bibliographic Details
Main Authors LI, HUIJIE, SOLLIS, STEVEN, L, NEVINS, NEYSA, EVANS, BRIAN, WALL, MICHAEL, D, ANDERSON, NIALL, BUSCH-PETERSEN, JAKOB, PALOVICH, MICHAEL, R, BULLION, ANN M
Format Patent
LanguageEnglish
French
German
Published 07.11.2012
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Disclosed are 4-amino-2-butenamides of Formula (I) having pharmacological activity, pharmaceutical compositions containing them, and methods for the treatment of diseases mediated by the cathepsin C enzyme such as chronic obstructive pulmonary disease.
Bibliography:Application Number: EP20100808681