SUGAR CHAIN MARKER AS MEASURE OF DISEASE CONDITIONS OF HEPATIC DISEASES

The present invention is directed to developing a glycan markers capable of detecting a hepatic disease, and more specifically to developing a glycan marker indicating a hepatic disease-state. Furthermore, the present invention is also directed to developing a glycan marker capable of distinguishing...

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Main Authors ANGATA, TAKASHI, TOGAYACHI, AKIRA, SHIKANAI, TOSHIHIDE, SOGABE, MAKI, MIZOKAMI MASASHI, NARIMATSU, HISASHI, OHKURA, TAKASHI, TANAKA YASUHITO, KAJI, HIROYUKI, KUNO, ATSUSHI, OCHOU, MAKOTO, IKEHARA, YUZURU, HIRABAYASHI, JUN
Format Patent
LanguageEnglish
French
German
Published 23.05.2012
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Summary:The present invention is directed to developing a glycan markers capable of detecting a hepatic disease, and more specifically to developing a glycan marker indicating a hepatic disease-state. Furthermore, the present invention is also directed to developing a glycan marker capable of distinguishing hepatic disease-states with the progress of hepatocarcinoma. The present inventors identified, among the serum glycoproteins, glycopeptides and glycoproteins in which a glycan structure specifically changes due to a hepatic diseases including hepatocarcinoma and provide these as novel glycan markers (glycopeptide and glycoprotein) specific to hepatic disease-states.
Bibliography:Application Number: EP20100799822