Fc variants with altered binding to FcRn

The present application relates to optimized IgG immunoglobulin variants, engineering methods for their generation, and their application, particularly for therapeutic purposes.

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Bibliographic Details
Main Authors DESJARLAIS, JOHN, RUDOLPH, KARKI, SHER, BAHADUR, CHAMBERLAIN, AARON, DAHIYAT, BASSIL
Format Patent
LanguageEnglish
French
German
Published 25.04.2012
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present application relates to optimized IgG immunoglobulin variants, engineering methods for their generation, and their application, particularly for therapeutic purposes.
Bibliography:Application Number: EP20120150987