New chemical molecules that inhibit the splicing mechanism for the treatment of diseases resulting from splicing defects

The present invention relates to a process for the preparation of a compound of formula (I) or one of its pharmaceutically acceptable saltswherein alternatively:- Z is N, V is C, Y is N, X is C, T is C, U is C and W is C,- Z is C, V is C, Y is N, X is C, T is C, U is C and W is C,- Z is N, V is C, Y...

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Bibliographic Details
Main Authors SCHERRER, Didier, GARCEL, Aude, NAJMAN, Romain, TAZI, Jamal, MAHUTEAU, Florence, CAMPOS, Noëlie
Format Patent
LanguageEnglish
French
German
Published 30.11.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to a process for the preparation of a compound of formula (I) or one of its pharmaceutically acceptable saltswherein alternatively:- Z is N, V is C, Y is N, X is C, T is C, U is C and W is C,- Z is C, V is C, Y is N, X is C, T is C, U is C and W is C,- Z is N, V is C, Y is C, X is N, T is C, U is C and W is C,- Z is N, V is N and is in para of Z, Y is N, X is C, T is C, U is C and W is C,- Z is N, V is C, Y is N, X is N, T is C, U is C and W is C,said process comprising the following steps: (i) reacting a compound of formula (III) with a compound of formula (IV), and then (ii) recovering the compound of formula (I).
Bibliography:Application Number: EP20100757474