Expression of mammalian proteins in Pseudomonas fluorescens

The invention is a process for improved production of a recombinant mammalian protein by expression in a Pseudomonad, particularly in a Pseudomonas fluorescens organism. The process improves production of mammalian proteins, particularly human or human-derived proteins, over known expression systems...

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Bibliographic Details
Main Authors RETALLACK, DIANE, M, GAERTNER, FRANK, H, SHUTTER, ROBERT, SQUIRES, CHARLES, H, LEE, STACEY, LYNN, WATKINS, DAVID, C
Format Patent
LanguageEnglish
French
German
Published 15.08.2012
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
DERIVATIVES THEREOF
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
SUGARS
VINEGAR
WINE
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Summary:The invention is a process for improved production of a recombinant mammalian protein by expression in a Pseudomonad, particularly in a Pseudomonas fluorescens organism. The process improves production of mammalian proteins, particularly human or human-derived proteins, over known expression systems such as E.coli in comparable circumstances. Processes for improved production of isolated mammalian, particularly human, proteins are provided.
Bibliography:Application Number: EP20110176612