FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES

Compounds and methods are disclosed that are useful for noninvasive imaging in the near-infrared spectral range. The cyanine compounds of Formula I are presented: wherein Q is a portion of a polymethine bridge selected from the group consisting of: Also included are bioconjugates of the compounds of...

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Bibliographic Details
Main Authors DRANEY, DANIEL R, XU, XINSHE
Format Patent
LanguageEnglish
French
German
Published 22.02.2012
Subjects
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Summary:Compounds and methods are disclosed that are useful for noninvasive imaging in the near-infrared spectral range. The cyanine compounds of Formula I are presented: wherein Q is a portion of a polymethine bridge selected from the group consisting of: Also included are bioconjugates of the compounds of Formula I, methods of labeling biomolecules with the compounds, and methods of imaging.
Bibliography:Application Number: EP20100715630