2-Aminooxazole derivatives for use as TRPV1 antagonists for treating i.a. pain, inflammation, neurodegenerative diseases or gastrointestinal diseases

Compounds of formula (I) wherein R 1 , R 2 , R 4 , and W are defined in the description are TRPV1 antagonists with CNS penetration. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.

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Bibliographic Details
Main Authors VASUDEVAN, ANIL, BAYBURT, EROL, K, DAANEN, JEROME, F, VOIGHT, ERIC, SCHMIDT, ROBERT, G, KORT, MICHAEL, E, GOMTSYAN, ARTHUR, R, KYM, PHILIP, R, PERNER, RICHARD, J, KOENIG, JOHN, R, DIDOMENICO, STANLEY, JR
Format Patent
LanguageEnglish
French
German
Published 01.02.2012
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Summary:Compounds of formula (I) wherein R 1 , R 2 , R 4 , and W are defined in the description are TRPV1 antagonists with CNS penetration. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.
Bibliography:Application Number: EP20110176290