INDOLE DERIVATIVES FOR TREATING NEURODEGENERATIVE DISEASES

The invention relates to a compound of the following formula (I), or to a pharmaceutically acceptable salt thereof or to a stereoisomer or mixture of stereoisomers at any proportions, where: X1 is a CH2 or C=O group; X2 is a linear saturated or unsaturated carbohydrate chain with 8 to 24 carbon atom...

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Bibliographic Details
Main Authors FIGADERE, BRUNO, RAISMAN-VOZARI, RITA, CHAMPY, PIERRE, SCHMIDT, FANNY
Format Patent
LanguageEnglish
French
German
Published 11.01.2012
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to a compound of the following formula (I), or to a pharmaceutically acceptable salt thereof or to a stereoisomer or mixture of stereoisomers at any proportions, where: X1 is a CH2 or C=O group; X2 is a linear saturated or unsaturated carbohydrate chain with 8 to 24 carbon atoms; R1 is a hydrogen atom or an OH or (C1-C6)alkoxy group such as methoxy; and R2 is a CH3 or CH2 OR3 group, with R3 being a hydrogen atom or a (C1-C6)alkyl, CO-(C1-C6)alkyl or NH-(C1-C6)alkyl group. The invention also relates to the use of said compound as a drug, in particular for treating neurodegenerative diseases, and to a method for preparing same.
Bibliography:Application Number: EP20100705616