HETEROCYCLIC COMPOUNDS AS PHOSPHODIESTERASE INHIBITORS

Compounds of the formula (I), their derivatives, analogs, tautomeric forms, regioisomers, stereoisomers, polymorphs, solvates, intermediates, pharmaceutically acceptable salts, pharmaceutical compositions, N-oxides, metabolites and prodrugs thereof. These compounds are phosphodiesterase type 4 (PDE4...

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Main Authors NARAYANAN, SUKUNATH, SHARMA, GANAPAVARAPU, VEERA, RAGHAVA, ANDIAPPAN, LAVANYA, NARAYANAN, SHRIDHAR, VISHWAKARMA, LOLAKNATH, SANTOSH, SAXENA, SANJEEV, RAJAGOPAL, SRIDHARAN, BALASUBRAMANIAN, GOPALAN, THIRUNAVUKKARASU, SARAVANAN
Format Patent
LanguageEnglish
French
German
Published 26.10.2011
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compounds of the formula (I), their derivatives, analogs, tautomeric forms, regioisomers, stereoisomers, polymorphs, solvates, intermediates, pharmaceutically acceptable salts, pharmaceutical compositions, N-oxides, metabolites and prodrugs thereof. These compounds are phosphodiesterase type 4 (PDE4) inhibitors. They are useful in the treatment of a variety of allergic or inflammatory diseases including asthma, COPD, chronic bronchitis, atopic dermatitis, allergic rhinitis, allergic conjunctivitis, vernal conjuctivitis, psoriasis, rheumatoid arthritis, ulcerative colitis, Crohn's disease, uveitis, NASH and lupus.
Bibliography:Application Number: EP20100733285