Thermostable viral polymerases and methods of use

Thermostable viral polymerases exhibiting a combination of activities selected from, proofreading (3'-5') exonuclease activity, nick translating (5'-3') nuclease activity, synthetic primer-initiated polymerase activity, nick-initiated polymerase activity, reverse transcriptase ac...

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Bibliographic Details
Main Authors DIFRANCESCO, ROBERT, A, DHODDA, VINAY, K, SCHOENFELD, THOMAS, W, MEAD, DAVID, A
Format Patent
LanguageEnglish
French
German
Published 19.10.2011
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Thermostable viral polymerases exhibiting a combination of activities selected from, proofreading (3'-5') exonuclease activity, nick translating (5'-3') nuclease activity, synthetic primer-initiated polymerase activity, nick-initiated polymerase activity, reverse transcriptase activity, strand displacement activity, and/or decreased discrimination against incorporation of nucleotide analogs. Also provided are compositions including the polymerases, polynucleotides encoding the polymerases and methods of using the polymerases.
Bibliography:Application Number: EP20110165551