Device for selectively targeting cells within a three-dimensional specimen

The invention relates to an apparatus for electromagnetically affecting a particle of interest in a specimen, comprising (a) a stage capable of supporting the specimen; (b) a detector capable of resolving a particle of interest within the specimen, wherein the detector comprises a camera viewing a s...

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Bibliographic Details
Main Authors EISFELD, TIMOTHY M, PALSSON, BERNHARD O, KOLLER, MANFRED R
Format Patent
LanguageEnglish
French
German
Published 07.09.2011
Subjects
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
BEER
BIOCHEMISTRY
CALCULATING
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
COMPUTING
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
COUNTING
CULTURE MEDIA
ELECTROTHERAPY
ENZYMOLOGY
HANDLING RECORD CARRIERS
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MAGNETOTHERAPY
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PHYSICS
PRESENTATION OF DATA
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
RADIATION THERAPY
RECOGNITION OF DATA
RECORD CARRIERS
SPIRITS
TESTING
ULTRASOUND THERAPY
VINEGAR
WINE
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Summary:The invention relates to an apparatus for electromagnetically affecting a particle of interest in a specimen, comprising (a) a stage capable of supporting the specimen; (b) a detector capable of resolving a particle of interest within the specimen, wherein the detector comprises a camera viewing a shallow focal planar region and wherein the focal planar region can be refocused on different sections of the specimen; or wherein the detector comprises a camera viewing a shallow depth of field and wherein the detector can be automatically refocused to obtain different sectional images of the specimen; (c) a means for locating the particle of interest in three dimensions; (d) a means for focusing electromagnetic radiation to a focal volume within the specimen; and (e) a means for adjusting the relative positions of the stage and electromagnetic radiation focusing means, thereby positioning the particle of interest within the focal volume.
Bibliography:Application Number: EP20110001625