MTOR KINASE INHIBITORS FOR ONCOLOGY INDICATIONS AND DISEASES ASSOCIATED WITH THE MTOR/P13K/AKT PATHWAY

Provided herein is a method for preparing a compound of formula (II):wherein the method comprising contacting a compound of formula (VI):with R1-Y in a solvent, in the presence of a palladium catalyst, wherein said contacting occurs in the presence of a base, wherein R1, R2, R3and Y are as defined h...

Full description

Saved in:
Bibliographic Details
Main Authors PAPA, Patrick, HARRIS, Roy, L, MADAKAMUTIL Loui, PACKARD, Garrick, LEE, Branden, TEHRANI, Lida, ZHAO, Jingjing, MORTENSEN, Deborah, SANKAR, Sabita, SAPIENZA, John, SHEVLIN, Graziella, PARNES, Jason, XU, Weiming, FULTZ Kimberly, ELSNER, Jan, PERRIN-NINKOVIC, Sophie, RIGGS, Jennifer, NARLA, Rama K
Format Patent
LanguageEnglish
French
German
Published 18.01.2017
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:Provided herein is a method for preparing a compound of formula (II):wherein the method comprising contacting a compound of formula (VI):with R1-Y in a solvent, in the presence of a palladium catalyst, wherein said contacting occurs in the presence of a base, wherein R1, R2, R3and Y are as defined herein.
Bibliography:Application Number: EP20090759827