Fusion Proteins for Treatment of CNS

This disclosure relates to compositions capable of use in the treatment of spinal cord injuries and related disorders of the central nervous system (CNS), and in particular, compositions including proteoglycan degradation molecules and compositions capable of blocking and/or over coming the activity...

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Bibliographic Details
Main Authors GRUSKIN, ELLIOTT A, ZIMBER, MICHAEL P, ROY, GARGI, CAGGIANO, ANTHONY O, IACI, JENNIFER
Format Patent
LanguageEnglish
French
German
Published 07.09.2011
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:This disclosure relates to compositions capable of use in the treatment of spinal cord injuries and related disorders of the central nervous system (CNS), and in particular, compositions including proteoglycan degradation molecules and compositions capable of blocking and/or over coming the activity of neuronal growth inhibitory molecules, as well as fusion proteins which includes a proteoglycan degradation domain and a domain capable of blocking and/or over coming the activity of neuronal growth inhibitory molecules.
Bibliography:Application Number: EP20100184697