STABILIZED COMPOSITIONS FOR RECOMBINANTLY PRODUCED FACTOR VIII

A histidine-free composition comprising: a high purity factor VIII (r-factor VIII); arginine and/or sucrose; a surface-active agent to prevent or at least inhibit surface adsorption of factor VIII; an amount of calcium chloride for specific stabilization of factor VIII.

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Bibliographic Details
Main Authors RIPPNER, BRITA, AGERKVIST, IRENE, IVARSSON, ELSA, NILSSON, ULRIKA, OESTERBERG, JOSEFIN
Format Patent
LanguageEnglish
French
German
Published 29.06.2011
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A histidine-free composition comprising: a high purity factor VIII (r-factor VIII); arginine and/or sucrose; a surface-active agent to prevent or at least inhibit surface adsorption of factor VIII; an amount of calcium chloride for specific stabilization of factor VIII.
Bibliography:Application Number: EP20090782562