MACROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS

The present invention provides compounds having formula (I), and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of various disorders including inflammatory or autoimmune disorders, and disorders involving malignancy or increased angiogenesis,...

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Main Authors INOUE, ATSUSHI, KUBOI, YOSHIKAZU, KAWAKAMI, YOSHIYUKI, LI, XIANG-YI, EGUCHI, YOSHIHITO, CHIBA, KENICHI, FUJITA, MASANORI, LEMELIN, CHARLES-ANDRE, HARMANGE, JEANRISTOPHE, KOTAKE, MAKOTO, GUSOVSKY, FABIAN, GOTO, MASAKI, KAWADA, MEGUMI, KIMURA, AKIFUMI, BOIVIN, ROCH, MURAMOTO, KENZO, SHIROTA, HIROSHI, KAWAI, TAKATOSHI, JIANG, YIMIN, DU, HONG
Format Patent
LanguageEnglish
French
German
Published 13.04.2011
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides compounds having formula (I), and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of various disorders including inflammatory or autoimmune disorders, and disorders involving malignancy or increased angiogenesis, wherein R 1 -R 11 , t, X, Y, Z and n are as defined herein.
Bibliography:Application Number: EP20100075633