Method of vitamin production

• Main Authors: SAUCY, GABRIEL G, MILLIS, JAMES R, MCMULLIN, THOMAS W, MAURINA-BRUNKER, JULIE
• Format: Patent
• Language: English; French; German
• Published: 06.04.2011
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; AGRICULTURE; ANIMAL HUSBANDRY; BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; FISHING; FORESTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HUNTING; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; NEW PLANTS OR PROCESSES FOR OBTAINING THEM; ORGANIC CHEMISTRY; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; TRAPPING; VINEGAR; WINE

The invention relates to methods for producing farnesol or geranylgeraniol comprising: (a) culturing a microorganism in a fermentation medium to produce a product selected from the group consisting of farnesyl phosphate and farnesol or geranylgeranyl phosphate and geranylgeraniol, wherein the action of squalene synthase of said microorganism is reduced; and (b) recovering said product.