PYRROLO[2,3-D]PYRIMIDIN-2-YL-AMINE DERIVATIVES AS PKC-THETA INHIBITORS

The present invention relates to a pyrrolo[2,3-d]pyrimidin-2-yl-amine derivative according to formula (I) wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceutical composition compris...

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Main Authors WIJKMANS, JACOBUS CORNELIS HENRICUS MARIA, OHLMEYER, MICHAEL, TEERHUIS, NEELTJE, MIRANDA, HO, KOC-KAN, KINGSBURY, CELIA, CHAN, JUI-HSIANG, NEAGU, IRINA, ROUGHTON, ANDREW LAIRD, LOMMERSE, JOHANNES, PETRUS, MARIA, PLATE, RALF, DILLER, DAVID
Format Patent
LanguageEnglish
French
German
Published 16.03.2011
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to a pyrrolo[2,3-d]pyrimidin-2-yl-amine derivative according to formula (I) wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceutical composition comprising one or more of said pyrrolo[2,3-d]pyrimidine-2-ylamine derivatives and to their use in therapy, for instance in the treatment of PKC mediated disorders.
Bibliography:Application Number: EP20090729779