Methods and compositions involving let-7 miRNA molecules

The present invention concerns methods and compositions for introducing miRNA activity or function into cells using synthetic nucleic acid molecules. Moreover, the present invention concerns methods and compositions for identifying miRNAs with specific cellular functions that arc relevant to therape...

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Bibliographic Details
Main Authors SLACK, Frank J, Brown, David, Jarvis, Rich, Cheng, Angie, Ovcharenko, Dmitriy, Byrom, Mike, Kelnar, Kevin, Ford, Lance, Devroe, Eric
Format Patent
LanguageEnglish
French
German
Published 09.02.2011
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
CULTURE MEDIA
ELECTROTHERAPY
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MAGNETOTHERAPY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
RADIATION THERAPY
SPIRITS
ULTRASOUND THERAPY
VINEGAR
WINE
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Summary:The present invention concerns methods and compositions for introducing miRNA activity or function into cells using synthetic nucleic acid molecules. Moreover, the present invention concerns methods and compositions for identifying miRNAs with specific cellular functions that arc relevant to therapeutic, diagnostic, and prognostic applications wherein synthetic miRNAs and/or miRNA inhibitors are used in library screening assays.
Bibliography:Application Number: EP20100183560