ISOPRENE SYNTHASE VARIANTS FOR IMPROVED MICROBIAL PRODUCTION OF ISOPRENE

The present invention provides methods and compositions comprising at least one isoprene synthase enzyme with improved catalytic activity and/or solubility. In particular, the present invention provides variant plant isoprene synthases for increased isoprene production in microbial host cells. Biosy...

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Main Authors WELLS, DEREK, H, CERVIN, MARGUERITE, A, RIFE, CHRISTOPHER, LEE, MIASNIKOV, ANDREI, MCAULIFFE, JOSEPH C, BOTT, RICHARD, R, KELLIS, JAMES, WHITED, GREGORY, M, WEYLER, WALTER, PERES, CAROLINE, M
Format Patent
LanguageEnglish
French
German
Published 02.02.2011
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The present invention provides methods and compositions comprising at least one isoprene synthase enzyme with improved catalytic activity and/or solubility. In particular, the present invention provides variant plant isoprene synthases for increased isoprene production in microbial host cells. Biosynthetically produced isoprene of the present invention finds use in the manufacture of rubber and elastomers.
Bibliography:Application Number: EP20090735440