PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING

The invention provides novel inhibitors of hedgehog signaling that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula I:wherein A, X, Y R1, R2, R3, R4, m and n are as described herein.

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Bibliographic Details
Main Authors REYNOLDS, MARK, E, SAVAGE, SCOTT, J, DINA, MICHAEL, S, CASTANEDO, GEORGETTE, SUTHERLIN, DANIEL, P, BAO, LIANG, LALONDE, REBECCA, L, GUNZNER, JANET, L, WANG, SHUMEI, STANLEY, MARK, S, MALESKY, KIMBERLY
Format Patent
LanguageEnglish
French
German
Published 12.01.2011
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention provides novel inhibitors of hedgehog signaling that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula I:wherein A, X, Y R1, R2, R3, R4, m and n are as described herein.
Bibliography:Application Number: EP20090731060