QUINAZOLINONE DERIVATIVES AS TUBULIN POLYMERIZATION INHIBITORS

The present invention provides compounds of formula (I), their use as inhibitors of tubulin polymerization as well as pharmaceutical compositions comprising said compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, n, m and X have defined meanings.

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Bibliographic Details
Main Authors MEVELLEC, LAURENCE ANNE, BOURDREZ, XAVIER MARC, FREYNE, EDDY JEAN EDGARD, VIALARD, JORGE EDUARDO, ANGIBAUD, PATRICK RENE, MEYER, CHRISTOPHE, PASQUIER, ELISABETH THERESE JEANNE
Format Patent
LanguageEnglish
French
German
Published 15.12.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides compounds of formula (I), their use as inhibitors of tubulin polymerization as well as pharmaceutical compositions comprising said compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, n, m and X have defined meanings.
Bibliography:Application Number: EP20090724207