CHEMICAL COMPOUNDS HAVING ANTIVIRAL ACTIVITY AGAINST DENGUE VIRUS AND OTHER FLAVIVIRUSES

Use of chemical compounds obtained in silico for the preparation of pharmaceutical compositions to attenuate or inhibit Dengue virus infection. Particularly, through the interference or the modulation of several stages of viral replication cycle related with the entry of virus into host cells and th...

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Main Authors VERA ALVAREZ, ROBERTO, CHINEA SANTIAGO, GLAY, GUIROLA CRUZ, OSMANY, MAZOLA REYES, YULIET, FLEITAS SALAZAR, NORALVIS, HUERTA GALINDO, VIVIAN, MUSACCHIO LASA, ALEXIS
Format Patent
LanguageEnglish
French
German
Published 08.12.2010
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Summary:Use of chemical compounds obtained in silico for the preparation of pharmaceutical compositions to attenuate or inhibit Dengue virus infection. Particularly, through the interference or the modulation of several stages of viral replication cycle related with the entry of virus into host cells and the assembly of mature progeny virions. The invention also comprises the use of such pharmaceutical compositions for prophylactic and/or therapeutic treatment of infection caused by all four serotypes of Dengue virus and other flaviviruses.
Bibliography:Application Number: EP20090714439