SYSTEMS AND METHODS FOR IDENTIFYING A CULTURE AS POSITIVE FOR MICROORGANISMS WITH HIGH CONFIDENCE
Systems, methods, and apparatus for determining whether a culture in a vessel contains a plurality of microorganisms are provided. A normalization relative value is calculated for each respective measurement of a biological state of the culture between (i) the respective measurement and (ii) an init...
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Main Author | |
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Format | Patent |
Language | English French German |
Published |
13.05.2015
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Subjects | |
Online Access | Get full text |
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Summary: | Systems, methods, and apparatus for determining whether a culture in a vessel contains a plurality of microorganisms are provided. A normalization relative value is calculated for each respective measurement of a biological state of the culture between (i) the respective measurement and (ii) an initial biological state. For each fixed interval of time points, a derivative of the normalization relative values in the interval of time points is calculated, thereby forming a plurality of rate transformation values. For each set of rate transformation values in the plurality of rate transformation values, a measure of central tendency of the values in the set is computed, thereby forming a plurality of average relative transformation values. A determination whether the culture contains the microorganisms is made based on whether any calculated average relative transformation value exceeds a first threshold or whether an extent of growth exhibited by the culture exceeds a second threshold. |
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Bibliography: | Application Number: EP20080725773 |