BICYCLIC HETEROCYCLIC DERIVATIVE

The present invention relates to a compound of the following formula (I) or a pharmaceutically acceptable salt thereof, being useful as a renin inhibitor. [wherein R 1a is halogen, etc.; R 1m is H, etc.; G 1 is -N(R 1b )-, etc.; G 2 is -CO-, etc.; G 3 is -C(R 1c )(R 1d )-, etc.; G 4 is oxygen, etc.;...

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Bibliographic Details
Main Authors FUSANO, AKIRA, IKUMA, YOHEI, SAWAMURA, KIYOTO, IKEDA, JUNYA, NAKAI, YOSHIO, KIMURA, HIDENORI, YOSHIDA, KOZO, NAKAHIRA, HIROYUKI, FUKUDA, NOBUHISA, SUETSUGU, SATOSHI
Format Patent
LanguageEnglish
French
German
Published 27.10.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to a compound of the following formula (I) or a pharmaceutically acceptable salt thereof, being useful as a renin inhibitor. [wherein R 1a is halogen, etc.; R 1m is H, etc.; G 1 is -N(R 1b )-, etc.; G 2 is -CO-, etc.; G 3 is -C(R 1c )(R 1d )-, etc.; G 4 is oxygen, etc.; R 1b is optionally substituted C 1-6 alkyl, etc.; R 1c and R 1d are independently the same or different, H, etc.; R 3 is H, optionally substituted C 1-6 alkyl, etc.; R 3a , R 3b , R 3c and R 3d are independently the same or different, and a group: -A-B (said A is single bond, etc., and said B is H, etc.), etc.; and n is 1, etc.]
Bibliography:Application Number: EP20080863079