QUINOXALINE AND QUINOLINE DERIVATIVES AS KINASE INHIBITORS

A series of heteroaryl-substituted quinoxaline and quinoline derivatives, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or opht...

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Main Authors BUERLI, ROLAND, BUCKLEY, GEORGE, MARTIN, LOCK, CHRISTOPHER, JAMES, MACK, STEPHEN, ROBERT, TAIT, LAURA, JANE, PITT, WILLIAM, ROSS, RATCLIFFE, ANDREW, JAMES, KINSELLA, NATASHA, SHARPE, ANDREW, DAVENPORT, RICHARD, JOHN, WARRELLOW, GRAHAM, JOHN, LOWE, CHRISTOPHER, WILLIAMS, SOPHIE, CAROLINE, SABIN, VERITY, MARGARET, ALLEN, DANIEL, REES, RICHARD, MARIANNA, DILANI
Format Patent
LanguageEnglish
French
German
Published 29.09.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A series of heteroaryl-substituted quinoxaline and quinoline derivatives, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions, said substituted derivatives having the general formula
Bibliography:Application Number: EP20080865707