ANTI-HUMAN IL-21 MONOCLONAL ANTIBODIES

Human anti-human IL-21 monoclonal antibodies and the hybridomas that produce them are presented. Certain of these antibodies have the ability to bind native human IL-21, a mutant recombinat IL-21 protein and/or peptide regions of human IL-21. These human anti-IL-21 antibodies are useful in therapeut...

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Main Authors KREJSA, CECILE, M, YI, EUGENE, C, DILLON, STACEY, R, JASPERS, STEPHEN, R, RIXON, MARK, W, RAMSDELL, FREDERICK, J
Format Patent
LanguageEnglish
French
German
Published 18.08.2010
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Human anti-human IL-21 monoclonal antibodies and the hybridomas that produce them are presented. Certain of these antibodies have the ability to bind native human IL-21, a mutant recombinat IL-21 protein and/or peptide regions of human IL-21. These human anti-IL-21 antibodies are useful in therapeutic treatment of autoimmune and inflammatory diseases, particularly diseases mediated by T follicular helper cells, B cells TH cells or TH17 cells.
Bibliography:Application Number: EP20080878088