Serum bactericidal assay for N. meningitidis specific antisera
The present invention relates to the field of Serum Bactericidal Activity (SBA) assays for Gram negative bacteria, in particular N. meningitidis. The SBA assay is the most important method for measuring functional activity of scrum antibodies against meningococcus. In order to determine whether a su...
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Main Authors | , , , |
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Format | Patent |
Language | English French German |
Published |
21.07.2010
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention relates to the field of Serum Bactericidal Activity (SBA) assays for Gram negative bacteria, in particular N. meningitidis. The SBA assay is the most important method for measuring functional activity of scrum antibodies against meningococcus. In order to determine whether a subject or a population is seropositive against invasive meningococcus the SBA test should ideally be both sensitive and specific. The inventors have found the standard N. meningitidis serotype A and W SBAs can be significantly improved in this regard. |
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Bibliography: | Application Number: EP20100160317 |