DUAL-RECOGNITION IMMUNOASSAY FOR THE DETECTION OF ANTIBODIES

The invention relates to a dual-recognition immunoassay for the detection of antibodies specific to a target antigen in a sample which comprises contacting said target antigen with a sample suspected of containing said antibodies specific to said target antigen under conditions allowing the formatio...

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Bibliographic Details
Main Authors SANZ FERNANDEZ, ANTONIO JOSE, VELA OLMO, CARMEN, VENTEO MORENO, ANGEL ANTONIO
Format Patent
LanguageEnglish
French
German
Published 01.09.2010
Subjects
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Summary:The invention relates to a dual-recognition immunoassay for the detection of antibodies specific to a target antigen in a sample which comprises contacting said target antigen with a sample suspected of containing said antibodies specific to said target antigen under conditions allowing the formation of an antigen-antibody complex; adding a conjugate comprising said target antigen and a marker under conditions allowing the formation of an antigen-antibody-antigen/marker complex; and detecting said antigen-antibody-antigen/marker complex. The immunoassay can be used, among other applications, in the diagnosis of infections caused by pathogenic organisms with high sensitivity and specificity.
Bibliography:Application Number: EP20080805353