PYRIMIDINE HYDRAZIDE COMPOUNDS AS PGDS INHIBITORS

This invention is directed to a compound of formula (I): wherein R1, R2, R3, R4 and L1 are as defined herein, a pharmaceutical composition comprising the compound, and the use of the compound to treat allergic and/or inflammatory disorders, particularly disorders such as allergic rhinitis, asthma an...

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Main Authors STOKLOSA, GRZEGORZ, T, JIANG, JOHN, Z, FENNIE, MICHAEL, W, MU, LAN, PEDGRIFT, BRIAN, THURAIRATNAM, SUKANTHINI, VANDEUSEN, CHRISTOPHER, L, PRIBISH, JAMES, R, RAUCKMAN, BARBARA, SABOL, JEFFREY, S, ALDOUS, SUZANNE, C, JOHN, STANLY
Format Patent
LanguageEnglish
French
German
Published 26.12.2012
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:This invention is directed to a compound of formula (I): wherein R1, R2, R3, R4 and L1 are as defined herein, a pharmaceutical composition comprising the compound, and the use of the compound to treat allergic and/or inflammatory disorders, particularly disorders such as allergic rhinitis, asthma and/or chronic obstructive pulmonary disease (COPD).
Bibliography:Application Number: EP20080744426