QUINOLINONE DERIVATIVES AS PARP AND TANK INHIBITORS

The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, n, m and X have defined meanings.

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Bibliographic Details
Main Authors FREYNE, EDDY JEAN EDGARD, VIALARD, JORGE EDUARDO, PILATTE, ISABELLE NOELLE CONSTANCE, PONCELET, VIRGINIE SOPHIE, ROUX, BRUNO, MEYER, CHRISTOPHE, MEVELLEC, LAURENCE ANNE, ADELINET, CHRISTOPHE DENIS, MARCONNET-DECRANE, LAURENCE FRANCOISE BERNADETTE, BOURDREZ, XAVIER MARC, MACRITCHIE, JACQUELINE ANNE, OWENS, ANDREW PATE, STORCK, PIERRE-HENRI, DUFFY, JAMES EDWARD STEWART, ANGIBAUD, PATRICK RENE, PASQUIER, ELISABETH THERESE JEANNE
Format Patent
LanguageEnglish
French
German
Published 25.01.2012
Subjects
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Summary:The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, n, m and X have defined meanings.
Bibliography:Application Number: EP20080717511