NOVEL MACROMOLECULE TRANSDUCTION DOMAINS AND METHODS FOR IDENTIFICATION AND USES THEREOF

The present invention discloses novel macromolecule transduction domain (MTD) peptides which facilitate the traverse of a biologically active molecule across the cell membrane. Also disclosed are polynucleotides encoding the MTD peptides, methods of identifying the MTD peptides; methods of genetical...

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Main Authors LIM, JUNG HEE, KO, JAE SUN, DUONG, MINH TAM, KIM, JIN SOOK, DO, THI THUY NGA, JO, DAE WOONG, PARK, KYUNG MI, DO, THI LAN PHUONG, SONG, JIN KYUNG
Format Patent
LanguageEnglish
French
German
Published 09.12.2009
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The present invention discloses novel macromolecule transduction domain (MTD) peptides which facilitate the traverse of a biologically active molecule across the cell membrane. Also disclosed are polynucleotides encoding the MTD peptides, methods of identifying the MTD peptides; methods of genetically engineering a biologically active molecule to have cell permeability by using the MTD peptides, methods of importing a biologically active molecule into a cell by using the MTD peptides, and uses thereof.
Bibliography:Application Number: EP20080712219